CypB-CD147 Signaling Is Involved in Crosstalk between Cartilage and FLS in Collagen-Induced Arthritis

<div>Gene expressions of MMPs, CypB, CD147, and inflammation-related genes in normal and CIA cartilage. Normal cartilage explants were treated with vehicle and 10 ng/mL IL-1<i>α</i>, and CIA cartilages were treated with vehicle, 10 ng/mL IL-1<i>α</i>, and 10 ng/mL IL-1<i>α</i> plus 10 <i>μ</i>M dexamethasone, respectively, before collected for total mRNA extraction. All data were presented as a value relative to those in the first group. 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Mediators of Inflammation

fig1

Figure 1

Figure 1: CypB-CD147 Signaling Is Involved in Crosstalk between Cartilage and FLS in Collagen-Induced Arthritis 