TLR7 Polymorphism (rs179008 and rs179009) in HIV-Infected Individual Naïve to ART

Table 3

Frequency distribution of haplotypes of TLR7 polymorphisms (rs179008, Gln11Leu (A/T) and rs179009, IVS2-151 (A/G)) in HIV-infected individuals and healthy controls.

Haplotypes TLR7 (rs179008 and rs179009)	HIV-infected individuals; (%)	Healthy controls; (%)	value	OR (95% CI)
AA	75.33%	72.44%	—	Reference
AG	14.33%	16.8%	0.22	0.75 (0.48-1.18)
TA	7.00%	5.41%	0.43	1.35 (0.64-2.84)
TG	3.33%	5.35%	0.32	0.66 (0.29-1.50)

 = number of chromosomes; % = haplotype frequency; age-adjusted odds ratios, and 95% CIs were derived from logistic regression models comparing the haplotype AA with other haplotypes.