Research Article

Albumin-to-Fibrinogen Ratio Independently Predicts 28-Day Mortality in Patients with Peritonitis-Induced Sepsis

Table 1

Baseline characteristics in septic patients.

ParametersTotal
()
Survivors
()
Nonsurvivors
()
value

Age (years)69 (52-82)69 (55-82)70 (52-79)0.31
Gender, (%)0.34
 Male154 (62.6)114 (61.0)40 (67.8)
 Female92 (37.4)73 (39.0)19 (32.2)
BMI (kg/m2)0.72
Comorbidities, (%)
 Hypertension67 (27.2)44 (23.5)23 (39.0)0.020
 Diabetes mellitus48 (19.5)34 (18.2)14 (23.7)0.35
 Cardiac disease25 (10.2)19 (10.2)6 (10.2)0.99
 Chronic renal disease25 (10.2)15 (8.0)10 (5.3)0.048
 Chronic lung disease23 (9.3)16 (8.6)7 (11.9)0.45
 Malignancy27 (11.0)20 (10.7)7 (11.9)0.80
 Cerebrovascular disease32 (13.0)24 (12.8)8 (13.6)0.89
Active smoking habits, (%)45 (18.3)35 (18.7)10 (16.9)0.76
Previous abdominal surgery, (%)89 (36.2)72 (38.5)17 (28.8)0.18
APACHE II score0.023
SOFA score<0.001
SAPS III score0.009
MCCI0.25
ASA physical status0.066
Septic shock, (%)91 (37.0)54 (28.9)37 (62.7)<0.001
Mean atrial pressure (mmHg)0.79
Body temperature (°C)0.14
Heart rate (per minute)0.095
Respiratory rate (per minute)0.13
Duration of operation (min)0.60
Mechanical ventilation, (%)182 (74.0)128 (68.4)54 (91.5)<0.001
Renal replacement therapy, (%)30 (12.2)18 (9.6)12 (20.3)0.028
Norepinephrine therapy, (%)63 (25.6)27 (14.4)36 (61.0)<0.001
Positive blood culture, (%)93 (37.8)69 (36.9)24 (40.7)0.60

BMI: body mass index; APACHE: Acute Physiology and Chronic Health Evaluation; SOFA: Sepsis-related Organ Failure Assessment; SAPS: Simplified Acute Physiology Score; MCCI: modified Charlson comorbidity index; ASA: American Society of Anesthesiologists. values were calculated by chi-square test, Fisher exact test, Mann–Whitney , or test. .