Notch-Hes1 Signaling Regulates IL-17A⁺γδ⁺T Cell Expression and IL-17A Secretion of Mouse Psoriasis-Like Skin Inflammation

Figure 2

Histopathological changes of experimental mice after consecutive 6 days’ treatment. (a) The epidermis of control mice was thin and consisted of only 1-2 layers of epidermal cells. (b) Model mice presented classic psoriasis-like histopathological features. (c) Intervention mice displayed significantly reduced epidermal hyperplasia and dermal inflammatory cell infiltration compared to model mice.

(a)

(b)

(c)