Research Article

Neutrophil-Lymphocyte Ratio in Predicting Infective Endocarditis: A Case-Control Retrospective Study

Table 1

Clinical and hematologic data of study population.

CharacteristicsPatients ()Controls () value

Age (years)0.86
Sex (man/female)463/2151630/8900.08
Comorbid conditions and predisposing factorsRheumatic heart disease95 (14.01%)
Congenital heart disease85 (12.54%)
Sepsis35 (5.16%)
Hypertension39 (5.75%)
Brain disease9 (1.33%)
Coronary artery disease74 (10.91%)
Nephropathy84 (12.39%)
Diabetes95 (14.01%)
Pulmonary infection12 (1.77%)
Cardiac insufficiency124 (18.29%)
Pathogens (no. (%))Culture positive230 (33.92%)
Culture negative448 (66.08%)
Gram-positive bacteria202 (86.70%)
Gram-negative bacteria16 (6.87%)
Fungus15 (6.43%)
Inflammatory markersNEU<0.001
LYM0.67
NLR<0.001
PCT (μg/L)
CRP (mg/L)

NLR: neutrophil-lymphocyte ratio; PCT: procalcitonin; CRP: C-reactive protein; NEU: neutrophils; LYM: lymphocytes.