Neutrophil-Lymphocyte Ratio in Predicting Infective Endocarditis: A Case-Control Retrospective Study

Table 5

Clinical and hematologic data compared between different clinical outcomes of IE patients.

Parameters	Good outcome ()	Bad outcome ()	value
Age			0.074
Sex (male)	377 (70.2%)	86 (60.99%)	0.036
Comorbid conditions
Coronary artery disease	58 (10.81%)	16 (11.34%)	0.853
Nephropathy	62 (11.55%)	22 (15.6%)	0.193
Diabetes	77 (14.34%)	18 (12.76%)	0.632
Pulmonary infection	9 (1.68%)	3 (2.13%)	0.721
Cardiac insufficiency	103 (19.18%)	21 (14.89)	0.241
Hypertension	29 (5.4%)	10 (7.09%)	0.443
Brain disease	7 (1.3%)	2 (1.42%)	1
Predisposing factors
Rheumatic heart disease	78 (14.53%)	17 (12.06%)	0.452
Congenital heart disease	68 (12.66%)	17 (12.06%)	0.847
Prosthetic valve	105 (19.55%)	28 (19.86%)	0.935
Degenerative valve disease	75 (13.97%)	14 (9.93%)	0.206
Implantable cardiac devices	32 (5.96%)	10 (7.09%)	0.619
Pathogens
Culture positive	170 (31.66%)	61 (43.26%)	0.010
Culture negative	367 (68.24%)	80 (56.74%)	—
Gram-positive bacteria	152 (28.31%)	47 (33.33%)	0.243
Gram-negative bacteria	12 (2.23%)	5 (3.55%)	0.375
Fungus	6 (1.12%)	9 (6.38%)	0.001
Inflammatory markers
NEU			<0.001
LYM			0.961
NLR			<0.001
PCT (μg/L)			<0.001
CRP (mg/L)			<0.001