Effects of the Glutamine Administration on T Helper Cell Regulation and Inflammatory Response in Obese Mice Complicated with Polymicrobial Sepsis

Figure 3

Percentages of helper T (Th) cell subpopulations in blood. Populations of Th cells were determined by CD4⁺ cells in CD3⁺ cells. As for subsets of Th cells, percentages of Th1 (interferon-γ-expressing cells), Th2 (interleukin (IL)-4-expressing cells), and Th17 cells (IL-17-expressing cells) among CD4⁺ lymphocytes were analyzed. Regulatory T (Treg) cells are presented as the percentage of CD25⁺Foxp3⁺ cells among CD4⁺ lymphocytes. SH: sham-operated group; SS: sepsis group with saline; SG: sepsis group with glutamine. Data are presented as the of the mean (SEM), for each group. Differences in groups at each time point were analyzed by a one-way ANOVA with the Tukey’s post-hoc test. The symbol “^#” significantly differs from the SH group; the symbol “” significantly differs from the SS group ().