Beneficial Effects of Rosmarinic Acid on IPEC-J2 Cells Exposed to the Combination of Deoxynivalenol and T-2 Toxin

Figure 2

Effects of (a) DON, (b) T-2, (c) DT2, and (d) RA on viability % of the differentiated IPEC-J2 cells measured by NR assay. Incubation times were 48 h and 72 h. Significant differences were found between untreated samples and cells exposed to 50 μmol/L DON or 20 nmol/L T-2. In the case of DT2 treatment, addition of 1 μmol/L DON and 5 nmol/L T-2 to IPEC-J2 cells did not influence cell viability significantly for 48 h and 72 h. RA appeared to be cytotoxic at higher concentrations (at 500 and at 1000 μmol/L). Data are presented as (, and ).

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