Effects of Shikonin on the Functions of Myeloid Dendritic Cells in a Mouse Model of Severe Aplastic Anemia

Figure 2

The PKM2+ mDC proportion of mDCs (PKM2+CD11c+/CD11c+) in the AA group was higher than those of the NC and TBI groups (, ). There was no significant difference between the NC and TBI groups (,). The PKM2 level is decreased in mDCs of the shikonin and CsA groups compared with the NS group (, ). There was no significant difference between the shikonin and CsA groups (). AA: aplastic anemia (); TBI: total body irradiation (); NC: normal control (); shikonin (); CsA: cyclosporin A (); NS: normal saline () ().