Research Article

Fibrinogen as a Prognostic Predictor in Pediatric Patients with Sepsis: A Database Study

Table 2

The laboratory parameters of patients with sepsis in the training set.

ParametersTotal
()
Survivors
()
Nonsurvivors
()

CRP (mg/L)55 (20, 125)55 (20, 117)60 (19, 165)0.265
Lac (mmol/L)2.2 (1.4, 3.4)2.05 (1.3, 3.1)3.7 (2.5, 6.6)<0.001
PT (s)12.6 (11.7, 13.9)12.6 (11.7, 13.7)13.2 (12, 16.1)0.005
INR1.12 (1.03, 1.22)1.12 (1.03, 1.21)1.17 (1.03, 1.38)0.036
APTT (s)34.5 (29.7, 40.9)34.3 (29.4, 40.6)37.1 (30.8, 46.6)0.004
Fib (g/L)3.1 (2.14, 4.18)3.2 (2.27, 4.25)2.02 (1.48, 3.06)<0.001
ALT (U/L)22 (14, 36)21 (14, 34)29 (17, 64)<0.001
TBIL (μmol/L)7.27 (4.7, 11.91)7.34 (4.7, 11.8)7.01 (4.75, 14.24)0.523
DBIL (μmol/L)2.1 (1.31, 3.67)2.1 (1.32, 3.52)2.23 (1.2, 4.82)0.285
LDH (U/L)492 (335, 850)485 (334, 831)547 (366.5, 1057)0.100
γ-GT (U/L)16 (11, 30)14.5 (11, 28)24 (14, 43)<0.001
Cr (μmol/L)26 (20, 34)25 (20, 33)30 (20, 44)0.005
BUN (mmol/L)3.4 (2.5, 4.7)3.3 (2.4, 4.4)4.5 (3.1, 8.5)<0.001
CK-MB (U/L)22 (14, 41)21 (13, 38)42 (19.5, 79.5)<0.001
PLT (×109/L)219 (119, 305)226 (132.5, 309)113 (29, 225)<0.001
WBC (×109/L)6.25 (4.59, 8.74)6.25 (4.64, 8.63)6.49 (3.94, 10.52)0.815

CRP: C-reactive protein; Lac: lactate; PT: prothrombin time; INR: international normalized ratio; APTT: activated partial thromboplastin time; Fib: fibrinogen; ALT: alanine aminotransferase; TBIL: bilirubin; DBIL: direct bilirubin; LDH: lactate dehydrogenase; γ-GT: γ-glutamyl transpeptidase; Cr: creatinine; BUN: blood urea nitrogen; CK-MB: creatine kinase-MB; PLT: platelet; WBC: white blood cell. Results are presented as median (interquartile range (IQR)).