Imbalance in PB IL-17-Secreting and Regulatory Cells in Pars Planitis Is Associated with Dysregulation of IFN-γ-Secreting Cells, Especially in Patients with Clinical Complications

Figure 1

Distribution of IFN- and IL-17-secreting cells in PB of pars planitis patients (PP) and healthy controls. Subjects with PP are characterized by decreased frequency of IFN-γ-producing T cells (a), increased frequency of IL-17-producing cells (b), and reduced frequency of both regulatory CD4+ and CD8+ T cells (c, d). There was no statistically significant difference in frequency of Breg cells between groups. C: healthy control group; PP: pars planitis. , , and .

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(b)

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(d)