Dextromethorphan Suppresses Lipopolysaccharide-Induced Epigenetic Histone Regulation in the Tumor Necrosis Factor-α Expression in Primary Rat Microglia

Figure 5

Illustration of the hypothetical scheme for how dextromethorphan attenuates LPS-induced enhancement of TNF-α, and hence may be involved in cascades of events leading to an inhibition of microglial cell activation.