Increased Death of Peripheral Blood Mononuclear Cells after TLR4 Inhibition in Sepsis Is Not via TNF/TNF Receptor-Mediated Apoptotic Pathway

<div>Western blot analysis of Bcl2, Bax, and GADPH levels in cultured PBMCs with/without LPS, rhHMGB1, and anti-TLR4 antibody treatment. The bar charts with one standard error show the ratio of Bcl2 to Bax (Bcl2 = B cell lymphoma 2; Bax = Bcl2-associated X; GADPH = glyceraldehyde-3-phosphate dehydrogenase; PBMCs = peripheral blood mononuclear cells; LPS = lipopolysaccharide; rhHMGB1 = recombinant human high-mobility group box 1; TLR = toll-like receptor).</div>

Mediators of Inflammation

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Figure 1

Figure 1: Increased Death of Peripheral Blood Mononuclear Cells after TLR4 Inhibition in Sepsis Is Not via TNF/TNF Receptor-Mediated Apoptotic Pathway 

Figure 1 | Increased Death of Peripheral Blood Mononuclear Cells after TLR4 Inhibition in Sepsis Is Not via TNF/TNF Receptor-Mediated Apoptotic Pathway 