Research Article
Increased Death of Peripheral Blood Mononuclear Cells after TLR4 Inhibition in Sepsis Is Not via TNF/TNF Receptor-Mediated Apoptotic Pathway
Table 1
Clinical characteristics in patients with sepsis (number,
error mean).
| | All patients () |
| | Age (years) | | | Male (%) | 12 (60.0) | | APACHE II score | | | History (%) | | | Chronic obstructive pulmonary disease | 2 (10.0) | | Heart failure | 2 (10.0) | | Hypertension | 8 (40.0) | | Diabetes mellitus | 7 (35.0) | | Old cerebral vascular accident | 3 (15.0) | | End-stage renal disease | 3 (15.0) | | Liver cirrhosis | 3 (15.0) | | Infection source | | | Pneumonia | 14 (70.0) | | Urinary tract infection | 5 (25.0) | | Others | 1 (5.0) | | Adverse event | | | Acute respiratory failure | 20 (100.0) | | Gastrointestinal bleeding | 1 (5.0) | | Acute renal failure | 9 (45.0) | | Shock | 11 (55.0) | | Thrombocytopenia | 6 (30.0) | | Jaundice | 3 (15.0) | | Bacteremia | 8 (40.0) | | 28-day mortality | 6 (30.0) |
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Abbreviations: APACHE = Acute Physiology and Chronic Health Evaluation.
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