Artesunate Restrains Maturation of Dendritic Cells and Ameliorates Heart Transplantation-Induced Acute Rejection in Mice through the PERK/ATF4/CHOP Signaling Pathway

<div>The mechanism of ART in BMDCs. ART reduces the generation of ROS to alleviate the endoplasmic reticulum stress and inhibits the maturation of DCs via reducing the expression of the PERK/ATF4/CHOP protein.</div>

Mediators of Inflammation

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Figure 7

Figure 7: Artesunate Restrains Maturation of Dendritic Cells and Ameliorates Heart Transplantation-Induced Acute Rejection in Mice through the PERK/ATF4/CHOP Signaling Pathway 

Figure 7 | Artesunate Restrains Maturation of Dendritic Cells and Ameliorates Heart Transplantation-Induced Acute Rejection in Mice through the PERK/ATF4/CHOP Signaling Pathway 