Research Article
Polymorphism of CD14 Gene Is Associated with Adverse Outcome among Patients Suffering from Cardiovascular Disease
Table 3
Association of genotype and allele distribution of SNPs in CD14, NF-κΒ, TLR2, and TLR4 and periodontal disease severity.
| | All patients | No or mild periodontitis | Severe periodontitis | value |
| | CD14: rs2569190 | | | | | | | | | | | CC (%) | 30.4 | 29.8 | 31.1 | 0.182 | | CT (%) | 46.6 | 44.8 | 48.5 | | TT (%) | 23.0 | 25.4 | 20.4 | | | | | | | C (%) | 53.7 | 52.2 | 55.3 | 0.186 | | T (%) | 46.3 | 47.8 | 44.7 |
| | NF-κΒ: rs28362491 | | | | | | | | | | | II (%) | 33.0 | 31.8 | 34.3 | 0.581 | | ID (%) | 51.4 | 51.5 | 51.1 | | DD (%) | 15.6 | 16.6 | 14.6 | | | | | | | I (%) | 58.7 | 57.6 | 59.9 | 0.341 | | D (%) | 41.3 | 42.4 | 40.1 |
| | TLR2: rs5743708 | | | | | | | | | | | AA (%) | 94.5 | 93.7 | 95.3 | 0.389 | | AG (%) | 5.4 | 6.1 | 4.7 | | GG (%) | 0.1 | 0.2 | 0 | | | | | | | A (%) | 97.2 | 96.8 | 97.6 | 0.305 | | G (%) | 2.8 | 3.2 | 2.4 |
| | TLR4: rs4986790 | | | | | | | | | | | AA (%) | 91.4 | 92.7 | 90.0 | 0.237 | | AG (%) | 8.4 | 7.1 | 9.8 | | GG (%) | 0.2 | 0.2 | 0.2 | | | | | | | A (%) | 95.6 | 96.3 | 94.9 | 0.175 | | G (%) | 4.4 | 3.7 | 5.1 |
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