Loss of GATA4 C-Terminus by p.S335X Mutation Modulates Coronary Artery Vascular Smooth Muscle Cell Phenotype

Figure 2

Deletion of GATA4 C-terminus enhanced RCSMC proliferation. The effects of GATA4 WT and MU overexpression on RCSMC proliferation was detected by MTS. The cells were treated with (a) 10% FBS for 24 h, (b–d) TNF-α (10 or 30 ng/ml) for 10 h, and (e–g) TNF-α (10 or 30 ng/ml) for 24 h. One-way ANOVA, , , versus WT, .

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