Tomatidine Improves Pulmonary Inflammation in Mice with Acute Lung Injury

<div>Tomatidine inhibited inflammatory mediators in mice. Tomatidine decreased the (a) gene expression of iNOS and (b) COX-2 in the lungs and suppressed (c) iNOS and COX-2 protein expressions. (d) The fold change in the expressions of COX-2 and iNOS protein was measured relative to the expression of <i>β</i>-actin, respectively. 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N group: normal control mice; LPS group: LPS treatment only; T5 group: 5 mg/kg tomatidine plus LPS; T10 group: 10 mg/kg tomatidine plus LPS.</div>

Mediators of Inflammation

fig5

Figure 5

Figure 5: Tomatidine Improves Pulmonary Inflammation in Mice with Acute Lung Injury 