Prophylactic Treatment of Probiotic and Metformin Mitigates Ethanol-Induced Intestinal Barrier Injury: In Vitro, In Vivo, and In Silico Approaches

Figure 1

Effect of probiotic V and Met unaided or in combination on ethanol-induced gut dysbiosis. (a) Body weight. (b) Relative colon weight to length ratio. Values are expressed as of six rats. Statistical analysis: one-way ANOVA followed by Tukey’s post hoc test. ^# and ^#### compared to the control group; , , , and compared with the ethanol-fed group; ^a compared with the E + probiotic V group; ^b compared with the E + Met group.

(a)

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