Involvement of circRNAs in Proinflammatory Cytokines-Mediated β-Cell Dysfunction

Figure 1

Changed expression profiles of circRNAs in cytokines-mediated pancreatic-β cell destruction. (a) The heat map of differentially expressed circRNAs in cytokines-treated pancreatic-β cells and control cells from microarray data. (b) Scatter plots showing differentially expressed circRNAs in cytokines-treated pancreatic-β cells and control cells. (c) Chromosomal frequency distribution of differentially expressed circRNAs. (d) Types of differentially expressed circRNAs. The circRNAs were classified into five types including exonic, antisense, intergenic, intronic, and sense overlapping. Blue and orange indicate upregulated and downregulated circRNAs, respectively.

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