Research Article

Effect of GLP-1/GLP-1R on the Polarization of Macrophages in the Occurrence and Development of Atherosclerosis

Table 1

Clinical and biochemical characteristics in HC and CHD groups.

HC groupCHD group value
()()

Age (years)0.002
Gender (male, female)27/2532/170.173
Smoking status (yes, no)14/3822/270.059
Drinking status (yes, no)6/468/410.486
HR (/bmp)75 (66.25~83.5)75 (64.5~83.5)0.534
SBP (mmHg)127.5 (120~141)139 (126.5~150.5)0.015
DBP (mmHg)78.5 (70.25~87.5)80 (72~88)0.809
PP (mmHg)51.5 (43.5~60)57 (46~68.5)0.087
TC (mmol/L)4.05 (3.54~5.04)4.21 (3.36~4.98)0.943
TG (mmol/L)1.33 (0.83~1.11)1.81 (1.31~2.84)0.009
HDL-c (mmol/L)0.98 (0.86~1.11)0.90 (0.73~1.14)0.043
LDL-c (mmol/L)2.22 (1.82~3.06)2.01 (1.54~2.94)0.213
GHbA1c (%)5.5 (5.3~5.9)5.8 (5.3~6.75)0.126
T2DM (yes, no)5/4710/390.127

HC: health control; CHD: coronary heart disease; HR: heart rate; SBP: systolic blood pressure; DBP: diastolic blood pressure; PP: pulse pressure; TC: cholesterol; TG: triglyceride; HDL-c: high-density lipoprotein cholesterol; LDL-c: low-density lipoprotein cholesterol; GHbA1c: glycosylated hemoglobin A1c; T2DM: type 2 diabetes mellitus.