Impact of MMP2 rs243865 and MMP3 rs3025058 Polymorphisms on Clinical Findings in Alzheimer’s Disease Patients

Table 5

Analysis of association between MMP3 rs3025058 (-1171 5A/6A) genotypes and clinical findings.

Parameter	5A/5A	5A/6A	6A/6A	CM	DM	RM	OM
Age at onset, (y)				0.11/0.11	0.09/0.09	0.52/0.53	0.045/0.048
MoCA score,				0.84/0.88	0.89/0.85	0.63/0.71	0.59/0.63

Abbreviations: CM: codominant model; DM: dominant model; RM: recessive model; OM: overdominant; SD: standard deviation; MoCA: Montreal Cognitive Assessment; : number; y: years. values were calculated using Welch’s corrected -test. values adjusted for sex and APOEε4 positivity. is considered statistically significant.