Research Article

Curcumin Antagonizes Glucose Fluctuation-Induced Renal Injury by Inhibiting Aerobic Glycolysis via the miR-489/LDHA Pathway

Figure 3

Effects of Cur on different ncRNAs related with the Warburg effect. We built a panel of 17 miRNAs and 8 lncRNAs that were involved in mediation of the Warburg effect. RT-qPCR results indicated that GF reduced the miR-489 content in the HEK-293 cell model, and a moderate dose of Cur (40 μM) could prevent this downregulation. Each error bar reflects the SEM of at least three independent sets.