Perilla Leaf Extract Attenuates Asthma Airway Inflammation by Blocking the Syk Pathway

Figure 3

Effects of PLE on the expressions and phosphorylation of Syk and its downstream signaling molecules in vivo. (a) The representative photomicrographs (×200), (b) percentage of positively stained cells, and (c) mean integrated optical density (MOD) of Syk staining ( independent slices from three mice in each group). (d) Representative photomicrographs (×200), (e) percentage of positively stained cells, and (f) MOD of p-Syk staining ( independent slices from three mice in each group). The expression of (g) Syk, (h) p-Syk, (i) PKC, (j) p-PKC, (k) p65, (l) p-p65, (m) cPLA₂, and (n) p-cPLA₂ in OVA-induced asthma mouse lung tissues was determined by WB (). ^##vs. the control group; and vs. the model group.

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