The Role of CARD9 Deficiency in Neutrophils

Figure 1

Neutrophils kill fungus via CARD9-dependent or independent mechanisms. Neutrophil-mediated killing mechanisms, either via CR3 or the Fcγ receptors, depended on fungal recognition. The killing capacity of CARD9-deficient neutrophils could be restored by opsonization of C. albicans with human IgG antibody.