Mediators of Inflammation

Research Article

[D-Ala2, D-Leu5] Enkephalin Inhibits TLR4/NF-κB Signaling Pathway and Protects Rat Brains against Focal Ischemia-Reperfusion Injury

Table 1

Physiological parameters.
VariablesShamACSFDADLE
Body weight (g)
Rectal temperature (°C)
 Preischemia 5 minutes
 Ischemia 10 minutes
 Ischemia 30 minutes
 Ischemia 60 minutes
MAP (mmHg)
 Preischemia 5 minutes
 Ischemia 10 minutes
 Ischemia 30 minutes
 Ischemia 60 minutes
Physiological parameters were taken before ischemia and within 60 minutes following ischemia. No significant differences were observed in body weight, rectal temperature, and MAP among groups at different times (). Data are expressed as (). DADLE: [D-Ala2, D-Leu5]; ACSF: artificial cerebrospinal fluid; MAP: mean arterial pressure; 1 mmHg, 0.133 kPa.