Review Article

The Association of Inflammatory Biomarker of Neutrophil-to-Lymphocyte Ratio with Spontaneous Preterm Delivery: A Systematic Review and Meta-analysis

Table 1

Characteristics of included studies assessing the association between NLR and preterm delivery.

AuthorsPublication yearCountrySample size (case/control)Study typeDefined preterm deliveryMean age of casesQuality assessment

Akgun et al. [22]2017Turkey238/545Prospective case-control37 weeksHigh
Akkar et al. [25]2016Turkey35/44Prospective case-control37 weeksLow
Cha et al. [29]2020South Korea28/308Prospective case-control37 weeksHigh
Daglar et al. [17]2016Turkey30/53Prospective case-control37 weeksLow
Farzaneh et al. [24]2019Iran109/110Cross-sectional37 weeksLow
Gezer et al. [28]2018Turkey229/178Retrospective case-control37 weeksHigh
Isik et al. [16]2015Turkey90/128Retrospective case-control34 weeksHigh
Kim et al. [27]2011South Korea102/73Retrospective case-control37 weeksHigh
Ma et al. [15]2020China105/210Retrospective case-control37 weeksHigh
Melissa et al. [19]2018USA137/145Retrospective case-control37 weeksLow
Mubark et al. [21]2015Iraq30/50Prospective case-control37 weeksLow
Ozel et al. [26]2020Turkey50/47Cross-sectional37 weeksHigh
Park et al. [23]2019South Korea19/49Retrospective cohort34 weeks34 [25-39]High
Sabarudin et al. [20]2016Indonesia33/33Cross-sectional37 weeksLow
Tamer et al. [18]2017Turkey74/45Case-control37 weeksLow

Indirectly conceived from methods, median (range).