Review Article
The Association of Inflammatory Biomarker of Neutrophil-to-Lymphocyte Ratio with Spontaneous Preterm Delivery: A Systematic Review and Meta-analysis
Table 1
Characteristics of included studies assessing the association between NLR and preterm delivery.
| Authors | Publication year | Country | Sample size (case/control) | Study type | Defined preterm delivery | Mean age of cases | Quality assessment |
| Akgun et al. [22] | 2017 | Turkey | 238/545 | Prospective case-control | 37 weeks | | High | Akkar et al. [25] | 2016 | Turkey | 35/44 | Prospective case-control | 37 weeks | | Low | Cha et al. [29] | 2020 | South Korea | 28/308 | Prospective case-control | 37 weeks | | High | Daglar et al. [17] | 2016 | Turkey | 30/53 | Prospective case-control | 37 weeks | | Low | Farzaneh et al. [24] | 2019 | Iran | 109/110 | Cross-sectional | 37 weeks | | Low | Gezer et al. [28] | 2018 | Turkey | 229/178 | Retrospective case-control | 37 weeks | | High | Isik et al. [16] | 2015 | Turkey | 90/128 | Retrospective case-control | 34 weeks | | High | Kim et al. [27] | 2011 | South Korea | 102/73 | Retrospective case-control | 37 weeks | | High | Ma et al. [15] | 2020 | China | 105/210 | Retrospective case-control | 37 weeks | | High | Melissa et al. [19] | 2018 | USA | 137/145 | Retrospective case-control | 37 weeks | | Low | Mubark et al. [21] | 2015 | Iraq | 30/50 | Prospective case-control | 37 weeks | | Low | Ozel et al. [26] | 2020 | Turkey | 50/47 | Cross-sectional | 37 weeks | | High | Park et al. [23] | 2019 | South Korea | 19/49 | Retrospective cohort | 34 weeks | 34 [25-39] | High | Sabarudin et al. [20] | 2016 | Indonesia | 33/33 | Cross-sectional | 37 weeks | | Low | Tamer et al. [18] | 2017 | Turkey | 74/45 | Case-control | 37 weeks | | Low |
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Indirectly conceived from methods, median (range). |