Predictive Ability of Serum IL-27 Level for Assessing Activity of Antineutrophil Cytoplasmic Antibody-Associated Vasculitis

Table 2

Linear regression analysis of inflammation-related variables and serum IL-27 and IL-18 levels with the cross-sectional BVAS.

Variables	Univariable			Multivariable
	Beta	95% CI	value	Beta	95% CI	value
WBC count	0.370	0.277, 1.033	0.001	-0.167	-1.172, 0.580	0.503
Neutrophil count	0.477	0.609, 1.504	<0.001	0.381	-0.166, 1.853	0.100
Lymphocyte count	-0.160	-3.845, 0.667	0.165
PLT count	0.304	0.004, 0.027	0.007	0.124	-0.008, 0.021	0.368
Serum albumin	-0.620	-8.647, -4.748	<0.001	-0.419	-7.410, -1.635	0.003
ESR	0.388	0.037, 0.125	<0.001	0.168	-0.022, 0.092	0.225
CRP	0.359	0.027, 0.107	0.001	-0.234	-0.098, 0.010	0.112
IL-27	0.393	0.006, 0.021	<0.001	0.221	0.001, 0.015	0.025
IL-18	0.158	-0.003, 0.018	0.170

IL: interleukin; BVAS: Birmingham vasculitis activity score; WBC: white blood cell; PLT: platelet; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein. Beta: standardised correlation coefficient.