Predictive Ability of Serum IL-27 Level for Assessing Activity of Antineutrophil Cytoplasmic Antibody-Associated Vasculitis
Table 4
Comparison of serum IL-27 and IL-18 levels according to the presence and absence of clinical manifestations.
Clinical manifestation
Serum IL-27
value
Serum IL-18
value
Absence
Presence
Absence
Presence
General manifestation
196.7 (191.4)
243.8 (251.2)
0.357
327.5 (167.5)
326.2 (151.4)
0.975
Cutaneous manifestation
213.2 (210.6)
220.1 (271.0)
0.936
323.0 (158.8)
366.9 (188.7)
0.496
Mucous and ocular manifestation
N/A
N/A
N/A
N/A
N/A
N/A
Otorhinolaryngologic manifestation
214.0 (201.1)
213.6 (233.8)
0.995
344.8 (185.0)
304.6 (122.7)
0.257
Pulmonary manifestation
214.5 (155.5)
213.3 (250.1)
0.980
325.3 (173.3)
328.2 (153.3)
0.938
Cardiovascular manifestation
214.3 (218.5)
204.8 (145.5)
0.932
326.3 (164.4)
339.8 (77.7)
0.872
Gastrointestinal manifestation
N/A
N/A
N/A
N/A
N/A
N/A
Renal manifestation
105.8 (163.5)
308.7 (210.8)
<0.001
270.4 (116.8)
376.7 (178.3)
0.003
Nervous systemic manifestation
222.5 (188.5)
190.6 (276.8)
0.630
337.2 (172.8)
299.8 (123.0)
0.367
Values are expressed as a . IL: interleukin; BVAS: Birmingham vasculitis activity score; N/A: not applicable. Since only three patients presented mucous and ocular manifestation, statistical analysis is not reliable. Since only one patients presented gastrointestinal manifestation, statistical analysis is not allowed.
