Predictive Ability of Serum IL-27 Level for Assessing Activity of Antineutrophil Cytoplasmic Antibody-Associated Vasculitis

Table 6

Correlation of inflammation-related variables and serum IL-27 and IL-18 levels with BVAS according to the time of diagnosis.

Variables	Correlation coefficient ()	value
Newly diagnosed AAV ()
WBC count	0.076	0.641
Neutrophil count	0.175	0.280
Lymphocyte count	-0.152	0.349
PLT count	0.104	0.522
Serum albumin	-0.488	0.001
ESR	0.206	0.202
CRP	0.209	0.195
IL-27	0.420	0.007
IL-18	0.431	0.005
Previously diagnosed AAV ()
WBC count	0.354	0.031
Neutrophil count	0.472	0.003
Lymphocyte count	0.006	0.972
PLT count	0.174	0.304
Serum albumin	-0.248	0.140
ESR	0.200	0.235
CRP	0.296	0.076
IL-27	0.367	0.025
IL-18	-0.018	0.915

IL: interleukin; ANCA: antineutrophil cytoplasmic antibody; BVAS: Birmingham vasculitis activity score; ANCA: antineutrophil cytoplasmic antibody; AAV: ANCA-associated vasculitis; WBC: white blood cell; PLT: platelet; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein.