A Variant of sNASP Exacerbates Lymphocyte Subset Disorder and Nephritis in a Spontaneous Lupus Model Sle1.Yaa Mouse

Figure 2

Pathological changes of the kidney and lung in mice. Representative HE-stained and PAS-stained kidney section (×400 magnification) and renal histopathology scores (a). Representative images of mouse IgG (b) and C3 (c) deposit in glomeruli from Sle1.Yaa and Sle1.Yaa.ΔsNASP mice (×400 magnification) and their respective fluorescence intensity grades. Representative H&E-stained lung section (×100 magnification) and pulmonary histopathology scores (d).

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