Evaluation of the Therapeutic Effects of the Hydroethanolic Extract of Portulaca oleracea on Surgical-Induced Peritoneal Adhesion

Figure 4

The effects of different doses of PO on adhesion formation and collagen deposition by histopathological evaluation using Masson’s trichrome staining; blue colour intensities (marked with yellow stars) represent fibrosis and collagen deposition. Pathological imaging; (a) normal group, (b) control group, (c) PO at the dose of 100 mg/kg, and (d) PO at the dose of 300 mg/kg. The highest rate of tissue fibrosis (blue colour) and collagen deposition was observed in the control group (b) compared to the normal group (a), which had the lowest fibrosis rate. Conversely, the blue colour intensities as a marker of fibrosis and collagen deposition in both doses of the extract groups (100 and 300 mg/kg) were significantly decreased compared to the control group (c, d).

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