Topical Administration of 15-Deoxy-<i>Δ</i><sup>12,14</sup>-Prostaglandin J<sub>2</sub> Using a Nonionic Cream: Effect on UVB-Induced Skin Oxidative, Inflammatory, and Histopathological Modifications in Mice

<div>Topical formulation containing 15d-PGJ<sub>2</sub> (TFcPGJ<sub>2</sub>) inhibits skin edema, myeloperoxidase activity, and MMP-9 activity triggered by UVB. The skin edema (a), myeloperoxidase activity (b), and MMP-9 activity (c) were determined in samples collected 12 h after the end of irradiation. Panel (c) presents data analysis of the activity of MMP-9 and a representative image. NC: negative control; PC: positive control; uTF: unloaded topical formulation. 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Mediators of Inflammation

fig2

Figure 2

Figure 2: Topical Administration of 15-Deoxy-<i>Δ</i><sup>12,14</sup>-Prostaglandin J<sub>2</sub> Using a Nonionic Cream: Effect on UVB-Induced Skin Oxidative, Inflammatory, and Histopathological Modifications in Mice 

Figure 2 | Topical Administration of 15-Deoxy-Δ12,14-Prostaglandin J2 Using a Nonionic Cream: Effect on UVB-Induced Skin Oxidative, Inflammatory, and Histopathological Modifications in Mice 