Research Article

Topical Administration of 15-Deoxy-Δ12,14-Prostaglandin J2 Using a Nonionic Cream: Effect on UVB-Induced Skin Oxidative, Inflammatory, and Histopathological Modifications in Mice

Figure 3

Topical formulation containing 15d-PGJ2 (TFcPGJ2) inhibits the depletion of endogenous antioxidants by UVB irradiation. The antioxidant capacity was measured using FRAP (a), ABTS (b), GSH (c), and total sulfhydryl (d) assays in samples collected 12 h after the end of irradiation. NC: negative control; PC: positive control; uTF: unloaded topical formulation. Bars are of 6 mice per group and are representative of two separate experiments. One-way ANOVA followed by Tukey’s test. versus the negative control group; # versus UVB-stimulated groups.
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