Topical Administration of 15-Deoxy-<i>Δ</i><sup>12,14</sup>-Prostaglandin J<sub>2</sub> Using a Nonionic Cream: Effect on UVB-Induced Skin Oxidative, Inflammatory, and Histopathological Modifications in Mice

<div>The UVB-triggered production of the cytokines was inhibited by topical formulation containing 15d-PGJ<sub>2</sub> (TFcPGJ<sub>2</sub>). The cytokines TGF-<i>β</i> (a) and IL-6 (b) were determined in skin samples collected 4 h after the irradiation. NC: negative control; PC: positive control; uTF: unloaded topical formulation. 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Mediators of Inflammation

fig5

Figure 5

Figure 5: Topical Administration of 15-Deoxy-<i>Δ</i><sup>12,14</sup>-Prostaglandin J<sub>2</sub> Using a Nonionic Cream: Effect on UVB-Induced Skin Oxidative, Inflammatory, and Histopathological Modifications in Mice 

Figure 5 | Topical Administration of 15-Deoxy-Δ12,14-Prostaglandin J2 Using a Nonionic Cream: Effect on UVB-Induced Skin Oxidative, Inflammatory, and Histopathological Modifications in Mice 