Topical Administration of 15-Deoxy-<i>Δ</i><sup>12,14</sup>-Prostaglandin J<sub>2</sub> Using a Nonionic Cream: Effect on UVB-Induced Skin Oxidative, Inflammatory, and Histopathological Modifications in Mice

<div>UVB irradiation triggers sunburn cell formation that is amenable by topical formulation containing 15d-PGJ<sub>2</sub> (TFcPGJ<sub>2</sub>) treatment. Sunburn cell (white arrows) counts were evaluated using hematoxylin and eosin-stained slices of skin samples collected 12 h after the end of irradiation. Stained slices were examined using light microscopy at 100x magnification. NC: negative control; PC: positive control; uTF: unloaded topical formulation. 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Mediators of Inflammation

fig6

Figure 6

Figure 6: Topical Administration of 15-Deoxy-<i>Δ</i><sup>12,14</sup>-Prostaglandin J<sub>2</sub> Using a Nonionic Cream: Effect on UVB-Induced Skin Oxidative, Inflammatory, and Histopathological Modifications in Mice 

Figure 6 | Topical Administration of 15-Deoxy-Δ12,14-Prostaglandin J2 Using a Nonionic Cream: Effect on UVB-Induced Skin Oxidative, Inflammatory, and Histopathological Modifications in Mice 