Research Article
Topical Administration of 15-Deoxy-Δ12,14-Prostaglandin J2 Using a Nonionic Cream: Effect on UVB-Induced Skin Oxidative, Inflammatory, and Histopathological Modifications in Mice
Figure 9
Topical formulation containing 15d-PGJ2 (TFcPGJ2) inhibits UVB irradiation-induced epidermal thickening. Epidermal thickness (double-edge white arrows) was evaluated using hematoxylin and eosin-stained slices of skin samples collected 12 h after the end of irradiation. Stained slices were examined using light microscopy at 40x magnification. NC: negative control; PC: positive control; uTF: unloaded topical formulation. Bars are of 6 mice per group and are representative of two separate experiments. One-way ANOVA followed by Tukey’s test. versus the negative control group; # versus UVB-stimulated compared groups.