Silencing IL12p35 Promotes Angiotensin II-Mediated Abdominal Aortic Aneurysm through Activating the STAT4 Pathway

Figure 2

IL12p35 silencing promotes Ang II-induced AAA formation and rupture. (a) Western blot analysis of IL12p35 expression after AAV-shIL12p35 injection in mice ( per group). (b) The survival curves of mice in the four groups ( per group). (c) The rupture rates of mice in the four groups ( per group). (d) Maximal abdominal aortic diameters of mice in the four groups ( per group). (e) Representative H&E and elastin staining in the four groups of mice ( per group). compared with the control group; compared with the AAA group.

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