Research Article
Silencing IL12p35 Promotes Angiotensin II-Mediated Abdominal Aortic Aneurysm through Activating the STAT4 Pathway
Figure 6
IL12p35 silencing exacerbates the Ang II-induced inflammatory response and SMC apoptosis. (a) Western blot analysis of IL12p35 expression after transfection with si-IL12p35 ( per group). (b–d) PCR analysis of IL-1β, IL-6, and TNF-α mRNA expression in the four groups ( per group). (e) Western blot analysis of the protein levels of Bcl-2 and Bax in the four groups ( per group). compared with the PBS group; compared with the Ang II group.
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