Silencing IL12p35 Promotes Angiotensin II-Mediated Abdominal Aortic Aneurysm through Activating the STAT4 Pathway

Figure 7

STAT4 silencing abolishes IL12p35-mediated inflammatory responses and SMC apoptosis. (a) Western blot analysis of STAT4 expression after transfection with si-STAT4 ( per group). (b–d) PCR analysis of IL-1β, IL-6, and TNF-α mRNA expression in the four groups ( per group). (e) Western blot analysis of the protein levels of Bcl-2 and Bax in the four groups ( per group). compared with the Ang II group.

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