MMP-9 Concentration in Peritoneal Fluid Is a Valuable Biomarker Associated with Endotoxemia in Equine Colic

Table 4

MMP-2, MMP-8, and MMP-9 concentrations in plasma and peritoneal fluid in the groups negative (, ≤6/19 points), questionable (, 7-9/19 points), or positive (, ≥10/19 points) for sepsis; median (lower quantile–upper quantile). Significant differences in comparison with the sepsis negative group are marked as .

Parameter	Negative	Questionable	Positive
MMP-2 (ng/ml) in plasma	55.3 (42.3–72.1)	47.0 (31.6–52.1)	69.4 (54.7–84.4)
MMP-2 (ng/ml) in peritoneal fluid	7.8 (0.0–23.90)	11.4 (1.3–24.0)	37.7 (0.0–90.4)
MMP-8 (ng/ml) in plasma	0.80 (0.00–1.99)	1.60 (0.45–2.40)	1.79 (0.00–5.47)
MMP-8 (ng/ml) in peritoneal fluid	0.00 (0.00–0.30)	0.29 (0.00–0.75)	0.05 (0.00–1.85)
MMP-9 (ng/ml) in plasma	107.8 (75.8–134.3)	86.0 (67.5–105.4)	143.8 (113.8–672.0)
MMP-9 (ng/ml) in peritoneal fluid	51.9 (18.9–74.8)	26.0 (7.5–182.1)	954.6 (119.4–8268.5)