Research Article
Heightened Local Th17 Cell Inflammation Is Associated with Severe Community-Acquired Pneumonia in Children under the Age of 1 Year
Table 2
Diagnostic power of cytokine thresholds at best performance.
| | Predictors | Cut-point (pg/ml) | Sensitivity (%) | Specificity (%) | AUC (95% CI) |
| | BAL IL-1β | 5.355 | 95.2% | 73.2% | 0.820 (0.706–0.934) | | BAL IL-6 | 4.345 | 71.4% | 82.9% | 0.771 (0.638–0.905) | | BAL IL-17 | 2.52 | 90.5% | 61.0% | 0.779 (0.662–0.896) | | BAL IL-1β+ IL-6+ IL-17 | 0.227 | 85.7% | 58.5% | 0.781 (0.662-0.899) | | Plasma IL-1β | 0.312 | 47.6% | 90.2% | 0.678 (0.555–0.800) | | Plasma IL-6 | 0.266 | 76.2% | 85.4% | 0.778 (0.661–0.895) | | Plasma IL-17 | 0.312 | 57.1% | 85.4% | 0.704 (0.581–0.828) | | Plasma IL-1β+ IL-6+ IL-17 | 0.246 | 71.4% | 82.9% | 0.747 (0.613-0.881) |
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