NRF2 Exerts Anti-Inflammatory Effects in LPS-Induced gEECs by Inhibiting the Activation of the NF-κB

Figure 8

NRF2 exerts anti-inflammatory effects in LPS-induced gEECs via TLR4/NF-κB pathway. Graphic description of this study. Proinflammatory cytokines induced by LPS through the TLR4/NF-κB pathway promoted NRF2 expression and transferred into the nucleus, and the nucleus NRF2 inhibited the expression of proinflammatory cytokines by directly binding to p65.