Exploration of Predictive Biomarkers for Postoperative Recurrence in Chronic Rhinosinusitis with Nasal Polyps Based on Serum Multiple-Cytokine Profiling

Table 3

ROC analysis results of different cytokines for predicting CRSwNP recurrence.

Cytokines	AUC (95% CI)	value	Cutoff value	Sensitivity	Specificity
Eotaxin	0.753 (0.642-0.865)	<0.001	43.6	0.667	0.806
G-CSF	0.665 (0.539-0.791)	0.016	134.0	0.500	0.861
IFN-α	0.636 (0.506-0.766)	0.047	1.4	0.444	0.861
IL-13	0.615 (0.484-0.746)	0.092	3.2	0.278	0.944
IL-17A	0.703 (0.576-0.830)	0.003	9.8	0.417	0.972
IL-6	0.666 (0.541-0.790)	0.016	1.0	0.44	0.861
MCP-1	0.642 (0.514-0.771)	0.038	47.6	0.417	0.833
RANTES	0.764 (0.654-0.873)	<0.001	6426.0	0.639	0.831

ROC: receiver-operating characteristic; CRSwNP: chronic rhinosinusitis with nasal polyps; AUC: area under the curve; CI: confidence interval; G-CSF: granulocyte colony-stimulating factor; IFN-α: interferon alpha; IL: interleukin; MCP: monocyte chemotactic protein; RANTES: regulated upon activation normally T expressed and presumably secreted.