Cayratia japonica Prevents Ulcerative Colitis by Promoting M2 Macrophage Polarization through Blocking the TLR4/MAPK/NF-κB Pathway

Figure 3

Effect of CJ on macrophage polarization in DSS-induced UC mice. (a) Loss of body weight after different administrations. (b) Colon length of mice after different administrations. (c) DAI score of mice after different administrations. (d) H&E staining for colon tissue damage after different administrations. Arrows show inflammatory infiltration, mucosal erosion, and crypt damage. (e) F4/80⁺CD11b⁺ cell and F4/80⁺CD206⁺ cell signals in the spleen shown by flow cytometer. (f) The expression of CD86 protein in the colon tissues of mice detected by immunohistochemistry. (g) The expression of IRF4 protein in the colon tissues of mice detected by immunohistochemistry. . ; ; ; .

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