CD226 Deficiency Alleviates Murine Allergic Rhinitis by Suppressing Group 2 Innate Lymphoid Cell Responses

Figure 2

The deficiency of CD226 attenuates OVA-induced inflammation in nasal mucosa and lung in a mouse model of AR. (a) Representative images of HE staining and histopathology.  μm. Quantification of thicknesses of CRECs in the nasal septum (). (b) PAS staining and quantification of goblet cells in the nasal mucosa ().  μm. (c) Representative images of HE-stained lung sections and evaluation of inflammation scores ().  μm. AR: allergic rhinitis; OVA: ovalbumin; NS: normal saline; CRECs: columnar respiratory epithelial cells; HE: hematoxylin and eosin; WT: wild type; KO: knockout. , , and .

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