The Association of Blood Urea Nitrogen to Creatinine Ratio and the Prognosis of Critically Ill Patients with Cerebral Infarction: A Cohort Study

Table 1

Comparisons of the baseline characteristics between the alive group and the dead group.

Variables	Total ()	Alive ()	Dead ()	Statistics
CHF, (%)					0.024
No	1508 (72.33)	1027 (73.88)	481 (69.21)
Yes	577 (27.67)	363 (26.12)	214 (30.79)
AF, (%)					0.686
No	1154 (55.35)	765 (55.04)	389 (55.97)
Yes	931 (44.65)	625 (44.96)	306 (44.03)
Diabetes mellitus, (%)					0.662
No	1451 (69.59)	963 (69.28)	488 (70.22)
Yes	634 (30.41)	427 (30.72)	207 (29.78)
Respiratory failure, (%)					<.001
No	1280 (61.39)	958 (68.92)	322 (46.33)
Yes	805 (38.61)	432 (31.08)	373 (53.67)
Renal failure, (%)					<.001
No	1623 (77.84)	1115 (80.22)	508 (73.09)
Yes	462 (22.16)	275 (19.78)	187 (26.91)
Malignant cancer, (%)					<.001
No	1792 (85.95)	1224 (88.06)	568 (81.73)
Yes	293 (14.05)	166 (11.94)	127 (18.27)
Thrombolytic, (%)					0.074
No	1777 (85.23)	1171 (84.24)	606 (87.19)
Yes	308 (14.77)	219 (15.76)	89 (12.81)
Anticoagulation, (%)					<.001
No	235 (11.27)	134 (9.64)	101 (14.53)
Yes	1850 (88.73)	1256 (90.36)	594 (85.47)
Hypertension, (%)					0.060
No	793 (38.03)	509 (36.62)	284 (40.86)
Yes	1292 (61.97)	881 (63.38)	411 (59.14)
Liver disease, (%)					<.001
No	1942 (93.14)	1321 (95.04)	621 (89.35)
Yes	143 (6.86)	69 (4.96)	74 (10.65)
Heart rate (time/min),					<.001
SBP (mmhg), M(Q1,Q3)	137 (116, 155)	138 (118,155)	134 (113,155)		0.031
DBP (mmhg), M (Q1, Q3)	70 (58, 83)	70 (58, 83)	70 (58, 82)		0.851
MAP (mmhg), M (Q1, Q3)	89 (76, 102)	89 (77, 103)	88 (75, 102)		0.284
Respiratory rate (time/min), M (Q1, Q3)	18.00 (15.00, 22.00)	18.00 (15.00, 21.00)	19.00 (15.00, 24.00)		<.001
Temperature (°C),					0.032
SOFA, M (Q1, Q3)	2.00 (1.00, 5.00)	2.00 (0.00, 4.00)	4.00 (1.00, 6.00)		<.001
SAPSII, M (Q1, Q3)	38.00 (30.00, 47.00)	35.00 (28.00, 44.00)	43.00 (35.00, 53.00)		<.001
OASIS,					<.001
WBC (K/μl), M(Q1, Q3)	10.30 (7.80, 13.80)	9.90 (7.70, 13.30)	11.50 (8.00, 15.80)		<.001
PLT (K/μl), M (Q1, Q3)	215.00 (160.00, 279.00)	217.00 (164.00, 276.00)	211.00 (153.00, 285.00)		0.209
Hemoglobin (g/dl),					<.001
RDW percent,					<.001
Hematocrit percent,					<.001
Creatinine (mg/dl), M (Q1,Q3)	1.00 (0.80, 1.40)	1.00 (0.80, 1.30)	1.10 (0.80, 1.60)		<.001
INR, M (Q1,Q3)	1.20 (1.10, 1.40)	1.20 (1.10, 1.30)	1.20 (1.10, 1.40)		<.001
BUN (mg/dl), M (Q1,Q3)	20.00 (14.00, 29.00)	19.00 (14.00, 27.00)	22.00 (16.00, 34.00)		<.001rep
Glucose (mg/dl), M (Q1,Q3)	130.00 (107.00, 167.00)	126.00 (106.00, 160.00)	136.00 (110.00, 184.00)		<.001
Bicarbonate (mEq/l),					<.001
Sodium (mEq/l),					0.076
Potassium (mEq/l),					0.013
Charlson comorbidity index, M (Q1,Q3)	5.00 (3.00, 8.00)	5.00 (3.00, 7.00)	6.00 (3.00, 8.00)		0.004
BUN/Cr, M (Q1, Q3)	19.38 (15.00, 24.44)	19.00 (15.00, 23.75)	20.00 (15.00, 25.71)		0.006

CHF: congestive heart failure; AF: atrial fibrillation; SBP: systolic blood pressure; DBP: diastolic blood pressure; MAP: mean arterial pressure; WBC: white blood cell; PLT: platelets; RDW: red cell distribution width; INR: International Normalized Ratio; SOFA: the Sequential Organ Failure Assessment; SAPSII: the Simplified Acute Physiology Score II; OASIS: the Oxford Acute Severity of Illness Score; BUN: blood urea nitrogen; Cr: creatinine.