The Association of Blood Urea Nitrogen to Creatinine Ratio and the Prognosis of Critically Ill Patients with Cerebral Infarction: A Cohort Study
Table 2
The association between BUN/Cr and mortality of participants with cerebral infarction.
Variables
Model 1
Model 2
RR (95% CI)
RR (95% CI)
BUN/CR
1.01 (1.01-1.02)
0.045
1.01 (1.01-1.02)
0.025
CHF
0.98 (0.78-1.24)
0.884
Respiratory failure
2.34 (1.90-2.87)
<0.001
2.50 (2.04-3.05)
<0.001
Renal failure
1.10 (0.86-1.41)
0.438
Malignant cancer
1.68 (1.27-2.22)
<0.001
1.72 (1.31-2.26)
<0.001
Anticoagulation
0.44 (0.33-0.60)
<0.001
0.46 (0.34-0.61)
<0.001
Liver disease
1.63 (1.11-2.37)
0.012
1.72 (1.19-2.49)
0.004
Heart rate
1.00 (1.00-1.01)
0.086
SBP
1.00 (1.00-1.01)
0.259
Respiratory rate
1.02 (1.00-1.03)
0.088
Temperature
0.95 (0.92-0.99)
0.007
0.95 (0.93-0.97)
<0.001
WBC
1.01 (1.00-1.03)
0.023
1.01 (1.01-1.03)
0.023
Hemoglobin
0.91 (0.76-1.08)
0.270
RDW percent
1.08 (1.03-1.14)
0.004
1.11 (1.06-1.16)
<0.001
Hematocrit percent
1.03 (0.97-1.10)
0.281
INR
0.98 (0.89-1.09)
0.740
Albumin
0.94 (0.79-1.11)
0.451
Glucose
1.01 (1.01-1.01)
0.008
1.01 (1.01-1.01)
0.002
Bicarbonate
0.97 (0.95-0.99)
0.033
0.96 (0.94-0.99)
0.001
Sodium
0.99 (0.98-1.00)
0.248
Potassium
1.05 (0.93-1.19)
0.402
Charlson comorbidity index
1.01 (0.98-1.05)
0.552
Mode l included variables with statistical difference between the alive group and the dead group. Model 2: multivariable logistic regression analysis adjusting respiratory failure, malignant cancer, anticoagulation, liver disease, temperature, WBC, RDW percent, glucose, and bicarbonate. CHF: congestive heart failure; SBP: systolic blood pressure; WBC: white blood cell; RDW: red cell distribution width; INR: International Normalized Ratio; BUN: blood urea nitrogen; Cr: creatinine.