Research Article

The Association of Blood Urea Nitrogen to Creatinine Ratio and the Prognosis of Critically Ill Patients with Cerebral Infarction: A Cohort Study

Table 2

The association between BUN/Cr and mortality of participants with cerebral infarction.

VariablesModel 1Model 2
RR (95% CI)RR (95% CI)

BUN/CR1.01 (1.01-1.02)0.0451.01 (1.01-1.02)0.025
CHF0.98 (0.78-1.24)0.884
Respiratory failure2.34 (1.90-2.87)<0.0012.50 (2.04-3.05)<0.001
Renal failure1.10 (0.86-1.41)0.438
Malignant cancer1.68 (1.27-2.22)<0.0011.72 (1.31-2.26)<0.001
Anticoagulation0.44 (0.33-0.60)<0.0010.46 (0.34-0.61)<0.001
Liver disease1.63 (1.11-2.37)0.0121.72 (1.19-2.49)0.004
Heart rate1.00 (1.00-1.01)0.086
SBP1.00 (1.00-1.01)0.259
Respiratory rate1.02 (1.00-1.03)0.088
Temperature0.95 (0.92-0.99)0.0070.95 (0.93-0.97)<0.001
WBC1.01 (1.00-1.03)0.0231.01 (1.01-1.03)0.023
Hemoglobin0.91 (0.76-1.08)0.270
RDW percent1.08 (1.03-1.14)0.0041.11 (1.06-1.16)<0.001
Hematocrit percent1.03 (0.97-1.10)0.281
INR0.98 (0.89-1.09)0.740
Albumin0.94 (0.79-1.11)0.451
Glucose1.01 (1.01-1.01)0.0081.01 (1.01-1.01)0.002
Bicarbonate0.97 (0.95-0.99)0.0330.96 (0.94-0.99)0.001
Sodium0.99 (0.98-1.00)0.248
Potassium1.05 (0.93-1.19)0.402
Charlson comorbidity index1.01 (0.98-1.05)0.552

Mode l included variables with statistical difference between the alive group and the dead group. Model 2: multivariable logistic regression analysis adjusting respiratory failure, malignant cancer, anticoagulation, liver disease, temperature, WBC, RDW percent, glucose, and bicarbonate. CHF: congestive heart failure; SBP: systolic blood pressure; WBC: white blood cell; RDW: red cell distribution width; INR: International Normalized Ratio; BUN: blood urea nitrogen; Cr: creatinine.