Identification of an Epigenetic Signature for Coronary Heart Disease in Postmenopausal Women’s PBMC DNA

Figure 2

The methylation array data was subjected to quality control. (a) The density figure shows the distribution of the complete array probes for the PC, PCG, and C groups. (b) Boxplots of the twelve samples’ β values. (c) A principal component analysis biplot of DNA methylation changes was used to highlight the data structure and sample link among the three sample groups. PC1 signifies the first principal component, whereas PC2 denotes the second main component. (d) A heat map illustrating three groupings of locations and samples that are differently methylation. The color shifts from red to blue, suggesting a strong to low correlation between the three samples.

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