Inhibition of CEBPB Attenuates Lupus Nephritis via Regulating Pim-1 Signaling

Figure 2

The knockdown of CEBPB alleviated the kidney damage in MRL/lpr mice. The mRNA and protein expression of CEBPB (a); 24-hour proteinuria level (b), serum BUN level (c), serum creatinine level (d), serum anti-dsDNA IgG level (e), and serum complement C3 level (f) in MRL/lpr mice injected with shCEBPB lentivirus. (CEBPB, CCAAT/enhancer-binding protein β; shCEBPB, CEBPB-short hairpin RNA; BUN, blood urea nitrogen).

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